Analisis Radiofarmaka Tc99m MDP pada Pasien Kanker Payudara di Daerah Tulang Lutut dan Panggul

Authors

  • Ira Fenta Jurusan Fisika, FMIPA, Universitas Andalas
  • Dian Milvita Jurusan Fisika, FMIPA, Universitas Andalas
  • Fadil Nazir PTKMR-BATAN Lebak Bulus Jakarta

DOI:

https://doi.org/10.25077/jfu.6.2.132-138.2017

Abstract

Telah dilakukan analisis radiofarmaka Tc99m MDP pada 25 orang pasien kanker payudara yang melakukan bone scan di daerah tulang lutut dan panggul menggunakan kamera gamma. Data diolah menggunakan teknik ROI dan Statistika 10. Hasil penelitian menunjukkan bahwa untuk tulang yang tidak terdapat metastasis: akumulasi radiofarmaka Tc99m MDP rata-rata pada lutut kanan sebesar 0,301 mCi, pada lutut kiri 0,297 mCi, pada panggul anterior 2,118 mCi, dan pada panggul posterior 1,914 mCi; bioditribusi radiofarmaka Tc99m MDP rata-rata pada lutut kanan sebesar 11,130 MBq, pada lutut kiri 10,974 MBq, pada panggul anterior 78,365 MBq, dan pada panggul posterior 70,815 MBq; presentase uptake radiofarmaka Tc99m MDP rata-rata pada lutut kanan sebesar 2,005 %, pada lutut kiri 1,977 %, pada panggul anterior 14,120 %, dan pada panggul posterior 12,759 %. Untuk tulang yang terdapat metastasis akumulasi radiofarmaka Tc99m MDP rata-rata pada lutut kanan sebesar 0,283 mCi, pada lutut kiri 0,303 mCi, pada panggul anterior 1,666 mCi, dan pada panggul posterior 1,665 mCi; bioditribusi radiofarmaka Tc99m MDP rata-rata pada lutut kanan sebesar 11,472 MBq, pada lutut kiri 11,210 MBq, pada panggul anterior 61,639 MBq, dan pada panggul posterior 83,746 MBq; presentase uptake radiofarmaka Tc99m MDP rata-rata pada lutut kanan sebesar 1,887 %, pada lutut kiri 2,020 %, pada panggul anterior 11,106 %, dan pada panggul posterior 11,102 %. Nilai akumulasi, biodistribusi, dan presentase uptake tertinggi terdapat pada panggul anterior. Secara umum nilai-nilai ketiga parameter lebih tinggi pada pasien yang didiagnosis suspect atau menderita metastasis daripada yang tidak terdapat metastasis.

Kata kunci :akumulasi, biodistribusi, kanker payudara,radiofarmaka Tc99m MDP,uptake.

Downloads

Published

2017-04-04

How to Cite

Fenta, I., Milvita, D., & Nazir, F. (2017). Analisis Radiofarmaka Tc99m MDP pada Pasien Kanker Payudara di Daerah Tulang Lutut dan Panggul. Jurnal Fisika Unand, 6(2), 132–138. https://doi.org/10.25077/jfu.6.2.132-138.2017

Issue

Vol. 6 No. 2 (2017)

Section

Articles

License

Copyright (c) 2017 Ira Fenta, Dian Milvita, Fadil Nazir

Creative Commons License

This work is licensed under a Creative Commons Attribution-NonCommercial 4.0 International License.

Please find the rights and licenses in JFU (Jurnal Fisika Unand).

1. License

The non-commercial use of the article will be governed by the Creative Commons Attribution license as currently displayed on Creative Commons Attribution-NonCommercial 4.0 International License.

2. Authors Warranties

The author warrants that the article is original, written by stated author(s), has not been published before, contains no unlawful statements, does not infringe the rights of others, is subject to copyright that is vested exclusively in the author and free of any third party rights, and that any necessary written permissions to quote from other sources have been obtained by the author(s).

3. User Rights

JFU's spirit is to disseminate articles published are as free as possible. Under the Creative Commons license, JFU permits users to copy, distribute, display, and perform the work for non-commercial purposes only. Users will also need to attribute authors and JFU on distributing works in the journal.

4. Rights of Authors

Authors retain the following rights:

  • Copyright, and other proprietary rights relating to the article, such as patent rights,
  • The right to use the substance of the article in future own works, including lectures and books,
  • The right to reproduce the article for own purposes, provided the copies are not offered for sale,
  • The right to self-archive the article.

5. Co-Authorship

If the article was jointly prepared by other authors, the signatory of this form warrants that he/she has been authorized by all co-authors to sign this agreement on their behalf, and agrees to inform his/her co-authors of the terms of this agreement.

6. Termination

This agreement can be terminated by the author or JFU upon two months notice where the other party has materially breached this agreement and failed to remedy such breach within a month of being given the terminating partys notice requesting such breach to be remedied. No breach or violation of this agreement will cause this agreement or any license granted in it to terminate automatically or affect the definition of JFU.

7. Royalties

This agreement entitles the author to no royalties or other fees. To such extent as legally permissible, the author waives his or her right to collect royalties relative to the article in respect of any use of the article by JFU or its sublicensee.

8. Miscellaneous

JFU will publish the article (or have it published) in the journal if the articles editorial process is successfully completed and JFU or its sublicensee has become obligated to have the article published. JFU may conform the article to a style of punctuation, spelling, capitalization, referencing and usage that it deems appropriate. The author acknowledges that the article may be published so that it will be publicly accessible and such access will be free of charge for the readers.