Perbandingan Dosimetri Perencanaan Radioterapi IMRT Menggunakan Fasilitas Beam Angle Optimization dan Teknik Manual Pada Kasus Kanker Nasofaring Stadium III
DOI:
https://doi.org/10.25077/jfu.13.1.170-176.2024Keywords:
Beam Angle Optimization, Dose Volume Histogram, Intensity Modulated Radiotherapy, Kanker NasofaringAbstract
Telah dilakukan perbandingan dosimetri perencanaan Intensity Modulated Radiotherapy (IMRT) menggunakan fasilitas beam angle optimization dan teknik manual pada kasus kanker nasofaring (KNF) stadium III. Penelitian bertujuan untuk menganalisis nilai Conformity Index (CI), Homogeneity Index (HI), dan dosis pada Organ at Risk (OAR) pada kurva Dose Volume Histogram (DVH), serta jumlah Monitor Unit (MU). Terdapat empat variasi perencanaan yang diuji, yaitu IMRT 5 lapangan manual (M5), IMRT 5 lapangan dengan beam angle optimization (O5), IMRT 7 lapangan manual (M7), dan IMRT 7 lapangan dengan beam angle optimization (O7). Secara statistik, hasil penelitian menunjukkan semua perencanaan pada PTV54, PTV60, dan PTV70 memiliki hasil yang hampir identik pada  keempat variasi perencanaan tersebut. Namun, perencanaan O5 didapatkan lebih unggul karena memiliki rata-rata nilai CI dan HI yang paling sesuai dengan pedoman International Commision on Radiation Units and Measurements (ICRU) Report 62, yaitu CI pada PTV54 (0,969±0,03), CI pada PTV60 (0,949±0,04), dan CI pada PTV70 (0,954±0,04), serta HI pada PTV54 (0,223±0,13), HI pada PTV60 (0,250±0,10), dan HI pada PTV70 (0,126±0,07). Perencanaan O5 juga memenuhi batas yang ditetapkan oleh Quantitative Analysis of Normal Tissue Effects in the Clinic (QUANTEC) untuk OAR. Oleh karena itu, perencanaan O5 dianggap sebagai metode utama yang paling optimal untuk kasus KNF stadium III, sementara M5 dapat dijadikan sebagai alternatif karena menggunakan Monitor Unit (MU) yang lebih sedikitReferences
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